Best Pharmacies in Lancaster, PA

Updated September 2026 · 5 businesses · Lancaster guide

Looking for pharmacies in Lancaster? Below you'll find 5 local options with their address, phone number, website and opening hours, plus practical advice on choosing the right one.

What they do: Retail and independent pharmacies for prescriptions, vaccines and over-the-counter medicine. Many offer drive-thru pickup, delivery and automatic refills.

This guide lists 5 pharmacies in and around Lancaster, spread across 2 ZIP codes. 3 have a phone number you can call directly from this page, 4 link to their own website, 4 are open on weekends. Listings are organized so you can compare them at a glance and contact them directly.

Top 5 Pharmacies in Lancaster

Listings are shown in no paid order: no business can pay to appear or to rank higher on this page.

1 Weis Markets Pharmacy

Open weekendsZIP 17601
Opening hours
Mon9 AM-1 PM, 1:30 PM-9 PM
Tue9 AM-1 PM, 1:30 PM-9 PM
Wed9 AM-1 PM, 1:30 PM-9 PM
Thu9 AM-1 PM, 1:30 PM-9 PM
Fri9 AM-1 PM, 1:30 PM-9 PM
Sat9 AM-1 PM, 1:30 PM-6 PM
Sun10 AM-1 PM, 1:30 PM-2 PM

CallDirections

2 Walgreens

Open 24/7ZIP 17601
Opening hours
MonOpen 24 hours
TueOpen 24 hours
WedOpen 24 hours
ThuOpen 24 hours
FriOpen 24 hours
SatOpen 24 hours
SunOpen 24 hours

CallDirections

3 Rite Aid

Open weekends
Opening hours
Mon9 AM-9 PM
Tue9 AM-9 PM
Wed9 AM-9 PM
Thu9 AM-9 PM
Fri9 AM-9 PM
Sat9 AM-6 PM
Sun9 AM-5 PM

CallDirections

4 CVS Pharmacy

Open weekendsZIP 17601
  • Address 630 Centerville Road, Lancaster, PA 17601
  • Website cvs.com
Opening hours
Mon8 AM-1:30 PM, 2 PM-8 PM
Tue8 AM-1:30 PM, 2 PM-8 PM
Wed8 AM-1:30 PM, 2 PM-8 PM
Thu8 AM-1:30 PM, 2 PM-8 PM
Fri8 AM-1:30 PM, 2 PM-8 PM
Sat9 AM-1:30 PM, 2 PM-6 PM
Sun9 AM-1:30 PM, 2 PM-5 PM

Directions

5 Queen Pharmacy

ZIP 17602
  • Address 965 East King Street, Lancaster, PA 17602

Directions

How to choose pharmacies in Lancaster

  • Check that the provider is licensed. You can look up any Pennsylvania medical license on the Department of State's PALS website.
  • Confirm that they accept your insurance plan and whether you need a referral from your primary care doctor.
  • Look at hospital affiliations. Many Lancaster practices belong to a larger health system, which makes referrals and records easier.
  • Ask about wait times for new patients, telehealth visits and after-hours coverage.
  • Read recent patient reviews, but focus on patterns (communication, billing, wait times) rather than one-off complaints.

Local tips for Lancaster

Lancaster County's Amish and Mennonite craftspeople make it a well-known source of handmade furniture, quilts and farm products, and many of these businesses close on Sundays.

Many of the best-rated businesses sit just outside the city in Manheim Township, East Lampeter or Lititz, so it's worth widening your search a few miles.

Lancaster is in Lancaster County, and local phone numbers use the 717 and 223 area codes. Popular areas include Downtown, Chestnut Hill, Cabbage Hill, Northeast, Southeast, West End, Musser Park.

Frequently asked questions

Which pharmacies in Lancaster are open on weekends?

According to their listed hours, these are open on Saturday or Sunday: Weis Markets Pharmacy, Walgreens, Rite Aid, CVS Pharmacy. Hours can change on holidays, so call before you go.

Which areas of Lancaster do these pharmacies cover?

The pharmacies on this list are located in ZIP codes 17601, 17602. Many businesses also serve nearby neighborhoods and suburbs, so ask when you call.

How do I know if a doctor is board certified?

You can check board certification for free on the American Board of Medical Specialties site (CertificationMatters.org), and verify a Pennsylvania license on the state's PALS lookup.

Do I need a referral to see pharmacies in Lancaster?

It depends on your insurance. HMO plans usually require a referral from your primary care physician, while PPO plans usually don't. Call your insurer or check your plan documents before booking.

What should I bring to my first appointment?

Bring a photo ID, your insurance card, a list of current medications and doses, any recent test results and a short list of questions you want to ask.

Business data for this page comes from © OpenStreetMap contributors (ODbL), reviewed and formatted by Pennsylvania Connection.

Information is collected from public sources and may change. Please confirm hours, prices and availability directly with each business. Business owner? Ask us to update your listing.