Best Pharmacies in Philadelphia, PA

Updated September 2026 · 10 businesses · Philadelphia guide

Looking for pharmacies in Philadelphia? Below you'll find 10 local options with their address, phone number, website and opening hours, plus practical advice on choosing the right one.

What they do: Retail and independent pharmacies for prescriptions, vaccines and over-the-counter medicine. Many offer drive-thru pickup, delivery and automatic refills.

This guide lists 10 pharmacies in and around Philadelphia, spread across 8 ZIP codes. 9 have a phone number you can call directly from this page, 8 link to their own website, 6 are open on weekends. Listings are organized so you can compare them at a glance and contact them directly.

Top 10 Pharmacies in Philadelphia

Listings are shown in no paid order: no business can pay to appear or to rank higher on this page.

1 CVS Pharmacy

Open weekendsZIP 19104
Opening hours
Mon7 AM-11 PM
Tue7 AM-11 PM
Wed7 AM-11 PM
Thu7 AM-11 PM
Fri7 AM-11 PM
Sat8 AM-11 PM
Sun8 AM-10 PM

CallDirections

2 Rite Aid

Open weekendsZIP 19142
Opening hours
Mon8 AM-10 PM
Tue8 AM-10 PM
Wed8 AM-10 PM
Thu8 AM-10 PM
Fri8 AM-10 PM
Sat8 AM-10 PM
Sun8 AM-9 PM

CallDirections

3 Aspire Pharmacy

Open weekendsZIP 19104
Opening hours
Mon9 AM-3 PM
Tue9 AM-7 PM
Wed9 AM-7 PM
Thu9 AM-7 PM
Fri9 AM-7 PM
Sat10 AM-3 PM
SunClosed

CallDirections

4 Apex Pharmacy

ZIP 19135
Opening hours
Mon9 AM-7 PM, Sa 09:00-2 PM
Tue9 AM-7 PM, Sa 09:00-2 PM
Wed9 AM-7 PM, Sa 09:00-2 PM
Thu9 AM-7 PM, Sa 09:00-2 PM
Fri9 AM-7 PM, Sa 09:00-2 PM

CallDirections

5 Suburban Pharmacy

Open weekendsZIP 19116
Opening hours
Mon9 AM-7 PM
Tue9 AM-7 PM
Wed9 AM-7 PM
Thu9 AM-7 PM
Fri9 AM-7 PM
Sat9 AM-3 PM
SunClosed

CallDirections

7 eMax Pharmacy

ZIP 19143
  • Address 4918 Baltimore Avenue, Philadelphia, PA 19143
  • Phone (267) 929-7277
Opening hours
Mon9 AM-5:30 PM, Sa 10:00-3 PM
Tue9 AM-5:30 PM, Sa 10:00-3 PM
Wed9 AM-5:30 PM, Sa 10:00-3 PM
Thu9 AM-5:30 PM, Sa 10:00-3 PM
Fri9 AM-5:30 PM, Sa 10:00-3 PM

CallDirections

9 Sunray Drugs

ZIP 19122
  • Address 1501 North Broad Street, Philadelphia, PA 19122
  • Website sunraydrugs.com
Opening hours
Mon9 AM-5 PM
Tue9 AM-5 PM
Wed9 AM-5 PM
Thu9 AM-5 PM
Fri9 AM-5 PM
SatClosed
SunClosed

Directions

10 ACME Pharmacy

Open weekendsZIP 19123
  • Address 180 West Girard Avenue, Philadelphia, PA 19123
  • Phone (215) 574-1221
Opening hours
Mon9 AM-9 PM
Tue9 AM-9 PM
Wed9 AM-9 PM
Thu9 AM-9 PM
Fri9 AM-9 PM
Sat9 AM-6 PM
Sun9 AM-4 PM

CallDirections

How to choose pharmacies in Philadelphia

  • Check that the provider is licensed. You can look up any Pennsylvania medical license on the Department of State's PALS website.
  • Confirm that they accept your insurance plan and whether you need a referral from your primary care doctor.
  • Look at hospital affiliations. Many Philadelphia practices belong to a larger health system, which makes referrals and records easier.
  • Ask about wait times for new patients, telehealth visits and after-hours coverage.
  • Read recent patient reviews, but focus on patterns (communication, billing, wait times) rather than one-off complaints.

Local tips for Philadelphia

Philadelphia has its own licensing rules that go beyond state law: the city's Department of Licenses and Inspections (L+I) issues contractor licenses, permits and trade licenses, so plumbers, electricians and contractors working in the city need an L+I license on top of any state registration.

SEPTA's subway, trolley and bus network covers most of the city, so check whether a business is near a Market-Frankford or Broad Street Line station if you don't drive. Street parking in Center City is limited and enforced by the Philadelphia Parking Authority.

Philadelphia is in Philadelphia County, and local phone numbers use the 215, 267 and 445 area codes. Popular areas include Center City, Old City, Fishtown, Northern Liberties, South Philly, University City, Manayunk, Chestnut Hill.

Frequently asked questions

Which pharmacies in Philadelphia are open on weekends?

According to their listed hours, these are open on Saturday or Sunday: CVS Pharmacy, Rite Aid, Aspire Pharmacy, Suburban Pharmacy, Broad and Snyder Pharmacy, ACME Pharmacy. Hours can change on holidays, so call before you go.

Which areas of Philadelphia do these pharmacies cover?

The pharmacies on this list are located in ZIP codes 19104, 19116, 19122, 19123, 19135, 19142, 19143, 19145. Many businesses also serve nearby neighborhoods and suburbs, so ask when you call.

How do I know if a doctor is board certified?

You can check board certification for free on the American Board of Medical Specialties site (CertificationMatters.org), and verify a Pennsylvania license on the state's PALS lookup.

Do I need a referral to see pharmacies in Philadelphia?

It depends on your insurance. HMO plans usually require a referral from your primary care physician, while PPO plans usually don't. Call your insurer or check your plan documents before booking.

What should I bring to my first appointment?

Bring a photo ID, your insurance card, a list of current medications and doses, any recent test results and a short list of questions you want to ask.

Business data for this page comes from © OpenStreetMap contributors (ODbL), reviewed and formatted by Pennsylvania Connection.

Information is collected from public sources and may change. Please confirm hours, prices and availability directly with each business. Business owner? Ask us to update your listing.